What Happens To My Promethease Genetic Data After Upload
Promethease Review Summary
Summary
Promethease provides detailed wellness reports for a price lower than most competitors. The interface could exist difficult for first time users.
This review is written with the intent to exist as unbiased as possible. However, it represents the opinion of an individual reviewer and is therefore subjective. Furthermore, at Nebula Genomics nosotros seek to educate the public about the benefits of Whole Genome Sequencing. Information about our Whole Genome Sequencing Dna test is therefore incorporated into the review.
October 6, 2021
Table of contents
- seven facts from our Promethease Review
- Promethease Introduction
- Overview
- Getting Started with Promethease
- How to Use Promethease
- Review of Promethease Privacy
- Promethease in the News
- Promethease Dna Reviews
- Pros and Cons
- Pros
- Cons
- Nebula Genomics
- Nebula Expand
- Whole-Genome Sequencing
Edited by Christina Swords, Ph.D.
7 facts from our Promethease Review
- Location: Promethease was recently acquired by MyHeritage which is located in Israel
- Products: Dna data upload for health reporting
- Reports: very detailed on disease risks, merely sometimes difficult to understand
- Event commitment: through the Promethease website
- Privacy: information deleted automatically afterward 45 days
- Cost: $12
- Alternatives: Nebula Genomics (gratuitous Dna upload and reporting based on latest scientific discoveries)
Promethease Introduction
Promethease is a website used for genome health reporting. The site was launched in 2008 and is based on the SNPedia wiki. Both websites were acquired in 2019 by the genealogy platform MyHeritage. Promethease and SNPedia accept get one of the most widely used sites for Deoxyribonucleic acid health reporting.
The company uses the SNPedia's extensive research library to inform users of their genetic variants. The SNPedia library contains health information on over 100,000 gene variants. Each entry in the SNPedia library is selected based on actual genetic information and results from peer-reviewed scientific research. Read more in our Promethease review!
Overview
Permit's start the review with an overview of the Promethease service. The company is a Deoxyribonucleic acid data analysis and literature retrieval organisation that does not offer Dna testing services. Instead, this visitor focuses on analyzing genetic markers in uploaded raw DNA information and providing detailed health reports. It does not offer any Dna ancestry or family tree maker services.
It is designed to be compatible with raw information from other genetic testing providers. The Promethease test is compatible with raw Dna information exports from Nebula Genomics, 23andMe, AncestryDNA, etc.
Their flagship product is a DNA health written report. This report is based on genetic data from academic research aggregated on SNPedia.com — a database of unmarried nucleotide polymorphisms (SNPs).
The health report is presented every bit a list of relationships between users' gene variants and health traits. Each item carries a cursory clarification, details about biology, and an assessment of the medical significance. This service tin can exist used to clarify medical history and genetic health risks based on family history.
The visitor is very transparent about the sources of its data. Users tin go from their results to the scientific studies behind those results with just a few clicks.
Each Promethease DNA report costs $12 and is generated in nether 15 minutes. Does Promethease offer discounts? Non normally. Nevertheless, you lot can upload multiple DNA raw information files at in one case for a reduced cost. The first upload costs $12 merely simultaneous additional files only toll but $4.
Want the most comprehensive sequencing to run through Promethease?
Nebula Genomics offers Whole Genome Sequencing, providing 10,000 times more information than near genotyping based genomics tests. Nebula offers variant interpretation tools, deep beginnings, and new reports every week. This data can also exist run through Promethease for additional analysis.
Getting Started with Promethease
Earlier we review Promethease reporting, let's accept a wait at how to become started using the service. Their website first greets users with its terms and weather. Users must agree to conditions, such as:
"I take the risk of learning that I may be at high risk for a debilitating illness"
And "I am aware that I am strongly encouraged to discuss my Promethease report with a doc"
After accepting the terms, users are asked to watch a tutorial video from 2016. The video can be viewed here:
Getting started takes only a few minutes, depending on the file size. Simply upload your raw DNA data (eastward.yard. files from 23andMe, AncestryDNA, VCF, etc.). Then purchase the report, and enter your contact information.
The company generates the report, and you will receive a link to it in an electronic mail.
How to Use Promethease
In this part of our Promethease review, we will examine the provided reporting. It offers sample reports for customers to review before uploading their data and buying reports. The report results are fabricated bachelor through a web browser. Sections of these can also exist downloaded to PDFs or exported to Excel spreadsheets.
Upon opening their results, users detect a listing of factor variants from their uploaded Dna file that Promethease analyzed.
Promethease reports are highly customizable. For example, users can search for specific medical weather similar AIDS or prostate cancer. Users tin besides filter by the number of academic references and the strength of the evidence. This is particularly useful because many other Deoxyribonucleic acid analysis services provide reports without explaining how they were produced.
Users can also search by keywords for specific genes, body parts, or conditions. For instance, yous tin search for variants in the MTHFR factor or BRCA1 gene, the latter of which is closely associated with breast cancer. You can likewise search for keywords like eyes or cancer.
Each study issue is assigned a repute that tin exist "good", "bad", or "not prepare." This indicates whether the user'south Dna has a positive or negative bear upon on health. For instance, whether specific SNPs analyzed decrease or increase the risk of a medical condition.
The report also gives each gene variant a score or "magnitude." Magnitudes are subjective measures of how interesting the gene variant is. Information technology indicates how of import it is for the user to pay attention to the issue.
For instance, the sample report of Alzheimer'due south shows a 2-times greater risk of the status with a magnitude of 3.5. That would be a BAD repute, meaning that the user has a SNP that increases the run a risk of developing Alzheimer'due south. The magnitude of 3.v suggests that the adventure increment is quite significant. Promethease suggests paying attention and maybe reaching out to a medical professional.
Users tin also filter their Promethease Deoxyribonucleic acid analysis reports data past category. The categories are broken up into the three subsets:
- Topics, such as acme, gout, and Ashkenazi Jewish
- Medical atmospheric condition, such equally alcoholism, indisposition, and kidney stones
- Clinvar Diseases, such as crack chin, Tay-Sachs disease, and Familial Mediterranean fever
All reports include cistron names and SNP IDs. If users click on them, they are taken to the SNPedia page. Here, users can review peer-reviewed research to learn more about each gene, variant, and medical condition.
Because the SNPedia database is and so comprehensive, Promethease suggests going over results with your doc, genetic counselor or another medical professional. In particular, if you are concerned about a item upshot.
Review of Promethease Privacy
Their privacy policy was updated after the site was acquired by MyHeritage. All personal data is transferred to and candy in the Usa.
Is Promethease safe? User Dna raw data files are deleted automatically after 45 days. Creating an account is optional. If users do not create an business relationship, their DNA data files are deleted subsequently 24 hours.
Will Promethease disembalm your personal data to third parties? The site says information technology may share users' information to third parties, such equally payment processors, that assist the company offer its services. It may also transfer user information in the effect of some other visitor acquisition, such as happened during the MyHeritage acquisition.
Promethease in the News
An article from 2018 published in the Seattle Times showed how a radiology resident at Baylor Academy Medical Center in Dallas got a faux positive. He tested himself on 23andMe but then submitted his raw data to Promethease and got a warning that he had a mutation linked to Lynch syndrome.
Promethease was a safe and independent calculator program adult by SNPedia that promised anonymity and devastation of information within 45 days. Users then realized that it was acquired past MyHeritage in 2019.
Promethease DNA Reviews
Amazon user R. Holzle makes a thorough customer review of their feel using 23andMe, AncestryDNA, and Promethease. They updated this review in 2019 after MyHeritage purchased the company. In general, the review is neutral in that the service provides useful insights on the risks of weather.
User reviews of Promethease on Reddit compare Promethease to Xcode Life.
Pros and Cons
Pros
- Full of detailed health information
- Less expensive than almost other health reporting services
- One single detailed wellness report generated rapidly
- Transparent almost scientific rigor. Can filter out weakly supported results.
Cons
- User interface not like shooting fish in a barrel to empathise
- Unregulated admission to DNA health data can be misconstrued
- Potential for false positives due to varying degrees of enquiry rigor
Nebula Genomics
We cease our review past comparing Promethease with Nebula Genomics and other Deoxyribonucleic acid testing and assay sites. Nebula Genomics stands out compared to other genomic wellness reporting services. We prioritize privacy above all else. We also offer whole genome sequencing, the nigh advanced genetic test. Information technology enables us to provide the most comprehensive reporting that is updated every week based on the latest enquiry.
Nebula Expand
Do you take DNA test results from other testing sites similar Ancestry or 23andMe? You tin can upload that data to Nebula for free. We will expand your Dna data and requite you access to a detailed report.
How do we achieve detailed reporting on genetic weather condition? Our expanded reports are generated statistical models to fill in the blanks left behind by typical Deoxyribonucleic acid genotyping tests. A genetic testing company like Promethease can provide information on some variants, simply our expanded reports tin can analyze almost all variants.
We live in a time of a genomic revolution that is changing our lives. Nosotros empower our users to stay informed virtually cut-edge enquiry and learn how it affects them. We curate the latest enquiry, personalize it based on your genomic information, and provide detailed reports through the Nebula Research Library.
Whole-Genome Sequencing
We also go beyond Dna information uploads. With our 30x Whole-Genome Sequencing service, we tin can determine 100% of your Deoxyribonucleic acid. With u.s.a., you lot become 10,000 times more data than with other services that, in contrast, simply read 0.one% of your genome!
Here is how Nebula compares with other DNA testing companies.
| | 23andMe | Beginnings | Promethease | Nebula Genomics |
| Blazon of Genome Reporting Service | Microarray-based genotyping & written report | Microarray-based genotyping & report | Health-oriented genome assay | Whole-Genome Sequencing (30x coverage) |
| Produced information | ~ 600,000 positions in the genome | ~ 700,000 positions in the genome | N/A | ~ 3,000,000,000 positions in the genome |
| Compatible with other sites | Can export data and apply it elsewhere | Tin can export information and use it elsewhere | Accepts all typical Deoxyribonucleic acid testing data (e.g. 23andMe, AncestryDNA and Nebula Genomics raw data) | Tin can consign information and use elsewhere or upload data from 23andMe/AncestryDNA to fill in gaps and learn more |
| Affiliated Companies | Yep | Yes | Endemic by MyHeritage | Deep ancestry reporting with total Y chromosome and mtDNA sequencing |
| Target Customer | Consumers who are interested in a express at-home genetic test | Consumers who are interested in a limited at-home genetic examination | Consumers who are interested in detailed health reports with references | Consumers who are interested in complete Dna testing and advanced reporting |
| User interface | Highly rated | Highly Rated | Less easy to understand than competitors | Highly Rated |
| Privacy Prioritized | No | No | No | Yes (learn more) |
| Cost | $99 or $199 | $99 or $119 | $12+ | $0, $99, $299 |
Other alternatives to Promethease you should consider are:
- 24Genetics (health tests)
- Genetic Genie, (free; for wellness information)
- GeneSight (pharmacogenomics Deoxyribonucleic acid testing)
- Genomelink (25 traits reported for gratis)
- HealthCodes DNA (personalized plans for wellness, diet, and fitness)
- myDNA (personalized fitness, diet, and medication plans)
- Xcode Life (fitness and health report)
Once y'all sympathise your detailed health report, many great supplement companies out there may help you lose weight and get healthy (you tin can read about many of them on our blog!) But exist conscientious! At that place are also dangerous experimental drugs out at that place like SR9009 and RAD 140 that are not approved for man consumption.
Did yous like our Promethease review? You lot can read more reviews on our web log and check out our complete guide to the best DNA test kit and other habitation tests.
Source: https://nebula.org/blog/promethease-review/
Posted by: delossantosherach.blogspot.com
0 Response to "What Happens To My Promethease Genetic Data After Upload"
Post a Comment